Letrozole: What is it and how does it work?

Letrozole is a medication commonly used in the treatment of breast cancer. It belongs to a class of drugs known as aromatase inhibitors, which work by inhibiting the enzyme aromatase. This enzyme is responsible for converting androgens into estrogen, a hormone that can promote the growth of hormone-receptor-positive breast cancer cells.

How does letrozole work?

By blocking the production of estrogen, letrozole helps to lower the levels of this hormone in the body. This can slow down or even stop the growth of breast cancer cells that rely on estrogen to grow and divide. In some cases, letrozole may be used as part of adjuvant therapy in postmenopausal women who have already undergone surgery to remove their breast cancer.

It’s important to note that letrozole is only effective in hormone-receptor-positive breast cancers, as it specifically targets the estrogen pathway. It is not recommended for use in women with hormone-receptor-negative breast cancer.

Side effects of letrozole

Like all medications, letrozole can cause side effects. Common side effects may include hot flashes, joint pain, fatigue, and nausea. More serious side effects such as bone thinning (osteoporosis) and an increased risk of fractures are also possible with long-term use of letrozole.

If you are prescribed letrozole, it’s important to discuss any concerns or potential side effects with your healthcare Letrozol Mylan Film 2.5mg provider. They can provide guidance on managing side effects and help monitor your response to the medication.

In conclusion, letrozole is a valuable tool in the treatment of hormone-receptor-positive breast cancer. By blocking estrogen production, it can help slow down the growth of cancer cells and improve outcomes for many patients. If you have questions about letrozole or its use in your treatment plan, don’t hesitate to speak with your healthcare team.